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What is Mesothelioma?

Mesothelioma is a cancer of the mesothelium, a thin layer of tissue that covers internal organs. It is an aggressive and deadly cancer, and while treatments are available, it is often not curable. Mesothelioma can affect different parts of the mesothelium, including the pleura (tissue surrounding the lungs), peritoneum (tissue in the abdomen), and tissue around the heart and testicles.

Symptoms

Mesothelioma is a type of cancer that affects the mesothelial cells, which are found in the lining of certain organs in the body. There are two main types of mesothelioma: pleural mesothelioma and peritoneal mesothelioma.

Pleural mesothelioma affects the tissue surrounding the lungs and can cause a range of symptoms, including chest pain, coughing, shortness of breath, and the presence of unusual lumps of tissue under the skin on the chest. It may also cause unexplained weight loss.

Peritoneal mesothelioma occurs in the tissue lining the abdomen and can cause abdominal pain, swelling, nausea, and weight loss.

It is important to note that the symptoms of mesothelioma may vary in severity and may not always be present. It is also important to remember that these symptoms can be caused by other medical conditions, and a proper diagnosis can only be made by a healthcare professional. If you are experiencing any of these symptoms, it is important to speak with your doctor for a proper evaluation and treatment.

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In addition to pleural and peritoneal mesothelioma, there are two other rare forms of the disease: pericardial mesothelioma and mesothelioma of the tunica vaginalis.

Pericardial mesothelioma affects the tissue surrounding the heart and can cause symptoms such as difficulty breathing and chest pain.

Mesothelioma of the tunica vaginalis occurs in the tissue surrounding the testicles and may be detected as swelling or a mass on a testicle.

It is important to note that these rare forms of mesothelioma are not well understood and the signs and symptoms of these forms of the disease may be unclear. If you are experiencing any unusual symptoms or changes in your health, it is important to speak with a healthcare professional for a proper evaluation and diagnosis.

Causes

Mesothelioma is caused by mutations in a cell's DNA that result in uncontrolled growth and the formation of a tumor. While the specific causes of these mutations are not fully understood, researchers have identified several factors that may increase the risk of developing the disease, including inherited conditions, environmental factors, health conditions, and lifestyle choices.

Risk Factors

Asbestos exposure is the main risk factor for mesothelioma. Asbestos is a naturally occurring mineral that has been used in various products because of its strength and resistance to heat. However, when asbestos is disturbed, such as during mining or the removal of asbestos insulation, it can release dust that can be inhaled or swallowed. Asbestos fibers that enter the body can irritate the mesothelial cells and potentially lead to mesothelioma, although the exact cause is not fully understood. It can take decades for mesothelioma to develop after asbestos exposure.

Not everyone with asbestos exposure will develop mesothelioma, which suggests that other factors may also be involved in determining the risk of the disease. These factors may include inherited conditions, living with someone who works with asbestos, a family history of mesothelioma, and radiation therapy to the chest. If you have a personal history of asbestos exposure, especially if it was significant or prolonged, or if you have other risk factors, it is important to talk to your healthcare provider about your risk of mesothelioma and any necessary screening or preventive measures.

Complications

Pleural mesothelioma, which affects the tissue surrounding the lungs, can spread and put pressure on structures in the chest, leading to complications such as difficulty breathing, chest pain, difficulty swallowing, and pressure on nerves and the spinal cord. It can also cause fluid accumulation in the chest, known as a pleural effusion, which can compress the lung and make breathing difficult.

Prevention

Reducing your exposure to asbestos may help lower your risk of developing mesothelioma. To reduce your exposure, you can take the following steps:

  • Find out whether you work with asbestos. Many people with mesothelioma were exposed to asbestos fibers at work. Some occupations that may involve asbestos exposure include asbestos miners, electricians, plumbers, pipefitters, insulators, shipyard workers, demolition workers, brake mechanics, selected military personnel, and home remodelers. Ask your employer if you have a risk of asbestos exposure on the job.
  • Follow your employer's safety regulations. To protect yourself from asbestos exposure at work, it is important to follow all safety precautions, such as wearing protective equipment. You may also be required to shower and change out of your work clothes before taking a lunch break or going home.
  • Be safe around asbestos in your home. Older homes and buildings may contain asbestos. In many cases, it is safer to leave the asbestos intact rather than attempting to remove it, as breaking up asbestos can release fibers into the air that can be inhaled. Consult experts trained to detect asbestos in your home and do not try to remove it yourself.

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